Rastogi P, Mudgal V, Pal V. S, Lohokare R


BACKGROUND: Suicidal ideation and attempt in context of depression is very common. Many studies
have demonstrated an association between suicidal behaviour and inammatory markers primarily
CRP. We explore a clinical inammatory marker (CRP) in psychiatric patients hospitalized in an acute adult inpatient facility
following suicidal attempt and ideation
AIMS: To compare hsCRP levels between depression patients with suicidal attempt and suicidal ideation.
Methodology: Comparison of 25 depression patients with suicidal attempt and 25 depression patients with suicidal ideation
was done, diagnosis as per ICD10. Hamilton Depression Rating Scale (HDRS-17), Beck Scale for Suicidal Ideation (BSSI),
Suicide behaviour Questionnaire- Revised (SBQ-R), were applied for assessment of depression and suicidality. Highly
sensitive CRP was measured using autoanalyzer.
RESULTS: hsCRP levels were signicantly high in depression patients with suicidal attempt (6.11 mg/dl) than depression with
suicidal ideation (2.14 mg/dl). Duration of illness, HAM-D, BSSI & SBQ-R scores correlated positively with hsCRP levels.
CONCLUSION: Depression with suicidal attempt patients demonstrated a statistically higher hs-CRP levels than depression
with suicidal ideation. Patients of depression with suicidal attempt have a strong positive correlation between hs-CRP levels
and HAM-D, BSSI & SBQ-R scores.


Suicide; Depression; C-reactive Protein; Inammatory Marker

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