PREVALENCE OF HELICOBACTER PYLORI IN NON-ULCER DYSPEPSIA PATIENTS

Rayees Ahmad Bhat, Dr. Dug Tariq Hassan, Dr. Liyaqat Nazir, Dr Shabir Ahmad Dar, Dr. Mohammad Zakiuddin

Abstract


BACKGROUND: Helicobacter pylori had unquestionably been observed by a number of workers since
Birchers rst description in 1874. Luck JM, Seth TN in 1924 documented urease activity in the human
stomach. It was thought that this urease activity originated in gastric mucosal cells and was not associated with the presence of
bacteria.
AIMS AND OBJECTIVE: 1.To know the prevalence of Helicobacter pylori in non-ulcer dyspepsia patients and to know the
prevalence of Helicobacter pylori in different clinical sub-groups of non-ulcer dyspepsia.
METHODS AND MATERIALS: study was conducted in Post-graduate Department of Surgery in Govt. Medical College Jammu
over a period of one year. Patients with non-ulcer dyspepsia, who attended the Department of Surgery either outpatient
department or indoor, were subjected to this study. Diagnosis of patients was made from the history of patients and upper G.I.
endoscopy. Overall seventy patients of non ulcer dyspepsia formed the material of the study. . Ultrasonography of abdomen
was done to rule out any pathology responsible for dyspepsia.
RESULT: th rd th The maximum numbers of non ulcer dyspepsia patients were seen in 4 decade of life followed by 3 and 5 decade of
th rd th life. 25.71% of cases were seen in 4 decade of life while 24.29% & 21.42% of cases were seen in 3 & 5 decade of life
rd respectively. The prevalence of H. pylori infection increases with age. Among 33 H. pylori positive patients, 7 patients are in 3
th th decade while 9, 8 and 6 patients are in 4 , 5th & 6 decade respectively. Prevalence of H. pylori infection in each age group
rd th th th increases with each decade 41.18%, 50%, 53.33%, 60% cases in 3 , 4 , 5 & 6 decades respectively.
CONCLUSION: Maximum percentage of non ulcer dyspepsia patients was in third decade. Prevalence of H pylori infection
increased with age. Prevalence of H pylori in males and females was not signicantly different. Prevalence of H pylori in lower
socio-economic class was signicantly different from middle and upper classes suggesting that poor hygiene and
overcrowding are responsible for increased prevalence of H pylori in patients of lower socio economic status.


Keywords


Dyspepsia, Helicobacter pylori, GERD, Peptic ulcer.

Full Text:

PDF

References


TalleyN, Non-ulcer dyspepsia: current approaches to diagnosis. American Family Physician, 1993; 47:6.

Jones RH, Lipleard S. Prevalence of symptoms of dyspepsia in the community. British Medical Journal, 1989; 298: 30-32.

Locke G. The epidemiology of functional gastrointestinal disorders in North America. Gastroenterology Clinics of North America, 1996; 25: 1-9.

Talley N, Zinsmester A, Scheck C. Dyspepsia and dyspepsia subgroups: a population based study. Gastroenterology, 1992; 102: 1259-68.

Talley NJ, Silverstein MD, Agréus L et al.AGA Technical Review: Evaluation of dyspepsia. Gastroenterology 1998; 114: 582-95.

Mc Namara D A, Buckley M, O'Mortain C A. Non-ulcer dyspepsia. Gastroenterol. Clin. Of North America. 2000; 29(4): 807-18.

Drossman DA. Functional gastrointestinal disorders and the Rome II process.

Gut 1995. AGA Technical Review: Evaluation of dyspepsia. Gastroenterology 1998; 114: 582-95; 45: II 2-5.

Talley NJ, Stanghellini V, Heading RC et al. Functional gastro duodenal disorders. Gut 1999; 45 (suppl 2):1137-42.

W H C Hu, S K Lam, et al .Functional dyspepsia: recent advances in Pathophysiology

HK Pract 1998; 20:327-334.


Refbacks

  • There are currently no refbacks.