SPECTRUM OF BLEEDING MANIFESTATIONS IN DENGUE FEVER PATIENTS IN A TERTIARY CARE HOSPITAL – THREE YEARS RECORD BASED STUDY.

Dr Veena Munavalli, Dr Ramu G

Abstract


Background: Dengue is a major public health concern present in almost all parts of India.  It presents with myriad of clinical findings. Many of the dengue fever cases are self-limiting, but the severity ranges from mild fever to life threatening complications, such as hemorrhage and shock. The current study is undertaken with an objective of describing the demographic profile and various bleeding manifestations as noted in the admitted dengue infected patients during the study period.

Methods: This is a three year case series study from 2015 to 2017 among 210 dengue serology positive patients aged >18 years, admitted in the department of General Medicine, Hanagal Shri Kumareshwar Hospital and Research Centre, S. Nijalingappa Medical College, Bagalkot during the months of June to September. Data was entered in MS excel and analysed using SPSS statistical package student version 23.  

Results: Out of the 210 patients, maximum number of cases belonged to the age group of 18-40 years. Young population were the ones who are commonly affected with dengue illness. There were 58.57% males and 41.42% females. Thrombocytopenia is seen in 109 patients while Bleeding manifestations occurred only in 18 patients with less than 20,000/cumm. Regarding the presentation of warning signs in the patients, abdominal pain was the most common sign, followed by Malena.

Conclusions:  Patients admitted with dengue fever were mostly young and males were predominantly seen. Thrombocytopenia was           reflected as a major laboratory investigating finding observed in almost half of the patients, but bleeding manifestations were minimal. Considering the spread of the disease and its complications, it is recommended that special preventive measures should be undertaken prior to the monsoon period.


Keywords


Dengue, Bleeding manifestations, Thrombocytopenia, Bagalkot

Full Text:

PDF

References


Brady OJ, Gething PW, Bhatt S (2012) Refining the global spatial limits of dengue virus transmission by evidence-based consensus. PLoS Negl Trop Dis 6: e1760

World Health Organization. Comprehensive guidelines for prevention and control of dengue and dengue hemorrhagic fever. New Delhi: WHO, SEARO; 2011.

Rodenhuis-Zybert IA, Wilschut J, Smit JM. "Dengue virus life cycle: viral and host factors modulating infectivity". Cellular and Molecular Life Sciences. 2010; 67 (16): 2773–86

World Health Organization (2009) Dengue Guidelines for Diagnosis, Treatment, Prevention and Control New Edition. Geneva: World Health Organization; 2009.

Martina BE, Koraka P, Osterhaus AD. "Dengue virus pathogenesis: an integrated view". Clinical Microbiology Reviews.2009; 22 (4): 564–81.

Whitehorn J, Farrar J. "Dengue". British Medical Bulletin. 2010; 95: 161–73.

Chajhlana SPS, Mahabhasyam RN, Varaprasada MSM, Anukolu RSR. Socio demographic and clinical profile of dengue fever cases at a tertiary care hospital, Hyderabad, Telangana. Int J Community Med Public Health 2017; 4: 2027-30.

Mehta SR, Bafna TA, Pokale AB. Demographic and clinical spectrum of dengue patients admitted in a tertiary care hospital. Med J DY Patil Vidyapeeth 2018; 11:128-31.

Pawar A, Chafekar N. Clinical Study of Diagnosed Cases of Dengue Fever in Tertiary Care Hospital in North Maharashtra. MVP Journal of Medical Sciences 2018; 5(1):58-63.

PDNN Sirisena, F Noordeen, L Fernando. A preliminary study on clinical profiles of dengue and dengue haemorrhagic fever suspected patients from two hospitals in the Western Province of Sri Lanka. Sri Lankan Journal of Infectious Diseases 2014 Vol.4 (2):99-107


Refbacks

  • There are currently no refbacks.