Dr. Prashanth Adiga



Benign Prostate Hyperplasia is a common disease in adult men and its incidence is age related. Prevalence of BPH is approximately 25% in men aged 40 to 49 years, 50% in men aged 50 to 59 years and 80% in men aged 70 to 79 years. 1 Renal failure and symptomatic benign prostatic hyperplasia (BPH) are two common health problems, they usually co-exist in 5.9–13.6% of the male population over 50 years of age.

TURP remains the gold standard surgical procedure for treatment of these cases. However, patients in renal failure have an increased risk for complications after TURP compared with patients with normal renal function, so we wanted to study the treatment outcome and complications associated with its management.

The purpose of this study was to determine the incidence of renal failure associated with BPH , effect of TURP in the morbilidity and mortality of patients with renal failure.


Prospective study from October 2017 to November 2019 Setting : Govt. Stanley Medical college and Hospital, Chennai, This is a clinical study of 80 cases of Benign prostatic hyperplasia in normal and in patients with non dialysis requiring renal failure who underwent


Once the serum creatinine values stabilized, the readings were recorded. Out of 40 patients who presented with elevated renal parameters, (patient with s.creatinine more than 1.3mg/dl ) ten patients subsequently showed fall in serum creatinine below 1.3, hence were considered along with normal patients in group 1. Because of this, the subsequent serum creatinine values of rest of 30  patients stabilized at a mean of 1.7 with a standard deviation of 0.3. Interestingly patients whose serum creatinine which stabilized at a value of more than 1.3, some of them had coexistent diabetes, hypertension. This might be an explanation that these patients have developed preexisting renal disease which was worsened by their developing benign prostatic hyperplasia

in group 1, out of 30  patients, three people had bleeding, one had retention, one perioperative death due to myocardial infarction was recorded, one patient had infection.

In all the patients with bleeding as complication, blood transfusion was given. Whereas in group 2, two people had bleeding out of 40 patients studied. ( 8% compared to 20% in group 1).


The incidence of associated with benign prostatic hyperplasia in our study was about 12.5%. .


Benign Prostate , TURP , renal failure

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Arrighi HM, Metter EJ, Guess HA, Fozzard JL. Natural history of benign prostatic hyperplasia and risk of prostatectomy. The Baltimore Longitudinal Study of Aging. Urology. 1991; 38(1 Suppl): p. 4-8.

Kumar R, Hill CM, McGeown MG. Acute renal failure in the elderly. Lancet. 1973 Jan; 1(7794): p. 90-91.

Wein A. campbell-walsh urology Wein AJ, editor.: elsevier; 2012.

Berry SJ, Coffey DS, Walsh PC, Ewing LL. The development of human benign prostatic hyperplasia with age. J Urol. 1984 Sep; 132(3): p. 474-479.

Nielsen KK, Nordling J, Hald T. Critical review of the diagnosis of prostatic obstruction. Neurourol Urodyn. 1994; 13(3): p. 201-217.

Hong SK, Oh JJ, Jeong SJ, Jeong CW, Kim IS, Park JM, et al. Prediction of outcomes after radical prostatectomy in patients diagnosed with prostate cancer of biopsy Gleason score ≥ 8 via contemporary multi (≥ 12)-core prostate biopsy. BJU Int. 2011 Jul; 108(2): p. 217-222.

Mebust WK, Holtgrewe HL, Cockett AT, Peters PC. Transurethral prostatectomy: immediate and postoperative complications. A cooperative study of 13 participating institutions evaluating 3,885 patients. J Urol. 1989 Feb; 141(2): p. 243-247

Roehrborn CG. BPH progression: concept and key learning from MTOPS, ALTESS, COMBAT, and ALF-ONE. BJU Int. 2008 Mar; 101 Suppl 3: p. 17-21. 47. Koch WF, Debruyne FM,. The outcome of renal ultrasound in the assessment of 556 consecutive patients with benign prostatic hyperplasia. J Urol. 1996 Jan; 155(1): p. 186-189

Sutaria PM, Staskin DR. Hydronephrosis and renal deterioration in the elderly due to abnormalities of the lower urinary tract and ureterovesical junction. Int Urol Nephrol. 2000; 32(1): p. 119-126.

Kojima M, Inui E, Ochiai A, Naya Y, Ukimura O, Watanabe H. Noninvasive quantitative estimation of infravesical obstruction using ultrasonic measurement of bladder weight. J Urol. 1997 Feb; 157(2): p. 476-479.


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