TO COMPARE THE EFFICACY OF THIOPENTONE VERSUS PROPOFOL AS ANAESTHETIC AGENTS AND COMPARE HEMODYNAMIC CHANGES AND RECOVERY PROFILE CAUSED BY THEM ON PATIENTS UNDERGOING ECT (ELECTROCONVULSIVE THERAPY).

Dr. Amey Ajit Sable, Dr. (Col) V. R. R Chari, Dr. Ashwini Khamborkar, Dr. Smruti Govekar

Abstract


The ECT is to provoke the generalised epileptic seizure by electrical stimulation of one or both hemisphere of the
cerebellum. Several anaesthetic drugs are used in ECT. Many drugs have anticonvulsant action and may decrease the
duration of ECT induce seizures . Use of larger doses of anaesthetic drugs will shorten duration of seizure activity and could adversely affect
efficiency of treatment. ECT can produce many hemodynamic changes and duration of seizures.
MATERIALS AND METHODS: Sixty patients of either sex, belonging to 18 to 65 years of age, ASA grade I and II were selected after applying
stringent inclusion and exclusion criteria. They were divided into two equal groups of 30 subjects each, using computer generated allocation.
RESULTS: This study was done to evaluate the hemodynamic stability, recovery profile and seizure duration. Propofol was better drug than
thiopentone sodium in all over aspect. Propofol was Haemodynamically stable than thiopentone as I observed with systolic blood pressure,
diastolic blood pressure, mean blood pressure as well as heart rate. The recovery profile was seen with modified Aldrete score. To shift the patient
from recovery score 8 is necessary with propofol it was achieved early than thiopentone sodium. Seizure duration was more with thiopentone and
less with propofol. There was no change in oxygen saturation with respect to drugs. Current stimulus was also constant for both drugs.


Keywords


Thiopentone , Propofol , ECT.

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References


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